Helper T cell diff erentiation enters a new era
نویسندگان
چکیده
JEM © The Rockefeller University Press $8.00 Vol. 203, No. 4, April 17, 2006 809–812 www.jem.org/cgi/doi/10.1084/jem.20060522 809 In the dark ages of T cell biology, we considered two fates for differentiated CD4+ T cells: T helper (Th)1 and Th2 cells. Now we know that the reality is much more complex and interesting. The newest Th cell subset produces the cytokine IL-17. New evidence shows that the IL-17–related cytokine IL-25 is essential for Th2 responses in two infectious disease models. Helper T cell diff erentiation enters a new era: Le Roi est mort; vive le Roi!
منابع مشابه
Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!
In the dark ages of T cell biology, we considered two fates for differentiated CD4+ T cells: T helper (Th)1 and Th2 cells. Now we know that the reality is much more complex and interesting. The newest Th cell subset produces the cytokine IL-17. New evidence shows that the IL-17-related cytokine IL-25 is essential for Th2 responses in two infectious disease models.
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